{"id":170531,"date":"2024-12-10T15:58:47","date_gmt":"2024-12-10T15:58:47","guid":{"rendered":"https:\/\/www.gorillagrillz.com\/can-osteoarthritis-be-relieved-in-dogs-with-cbd\/"},"modified":"2025-01-09T00:08:17","modified_gmt":"2025-01-09T00:08:17","slug":"can-osteoarthritis-be-relieved-in-dogs-with-cbd","status":"publish","type":"post","link":"https:\/\/www.gorillagrillz.com\/en\/can-osteoarthritis-be-relieved-in-dogs-with-cbd\/","title":{"rendered":"Can osteoarthritis be relieved in dogs with CBD?"},"content":{"rendered":"Osteoarthritis frequently occurs in canines, typically associated with pain and restricted mobility. Recently,<a href=\"\/?page_id=143930\"> CBD for dogs<\/a> (Cannabidiol) has emerged as a promising natural option to alleviate symptoms related to osteoarthritis in dogs. It is essential to emphasize the importance of consulting a veterinarian before administering <a href=\"\/?page_id=169604\">CBD to pets<\/a>, especially in the context of specific health conditions.\r\n<h2>What is osteoarthritis in dogs?<\/h2>\r\nOsteoarthritis is defined as a degenerative condition that affects the joints, marked by the deterioration of articular cartilage. This process can trigger symptoms such as pain, swelling, and a reduction in mobility. Although this disease can manifest in dogs of all breeds and ages, it tends to be more common in older animals.\r\n<h2>What is the function of cartilage?<\/h2>\r\nCartilage in dogs and other animals is a smooth layer that covers the bones in the joints, allowing frictionless movement and acting as a cushion during activities like jumping or running. Osteoarthritis in dogs is characterized by the progressive deterioration of this cartilage, diminishing its cushioning capacity and increasing wear. This condition is divided into:\r\n<ul>\r\n \t<li><strong>Primary osteoarthritis<\/strong>, common in older animals due to natural wear.<\/li>\r\n \t<li><strong>Secondary osteoarthritis<\/strong>, which occurs after injuries or diseases that damage the articular cartilage.<\/li>\r\n<\/ul>\r\n<h2>What are the symptoms of this disease in dogs?<\/h2>\r\nTo determine whether a dog is suffering from osteoarthritis, it is crucial to observe its behavior while moving, such as difficulty climbing stairs or playing. A dog experiencing joint pain will limit its movements, may limp, and exhibit behavioral changes, avoiding contact or even becoming aggressive. Advanced signs include locked joints, which further restrict mobility. Detecting these symptoms early allows for intervention before the dog\u2019s condition deteriorates significantly.\r\n<h2>Diagnosis of osteoarthritis in dogs<\/h2>\r\nIf you have noticed any of the symptoms mentioned, regardless of your dog\u2019s age, it is essential to consult a veterinarian. The veterinarian will conduct a detailed examination of your pet\u2019s joints. To confirm the diagnosis, they will also rely on X-rays, which can validate or rule out the specialist\u2019s initial hypotheses.\r\n<h2>How does CBD work in a pet\u2019s body?<\/h2>\r\nCBD is one of the many components found in cannabis. It is known for not having psychoactive effects, meaning it does not induce states of euphoria in pets. On the contrary, CBD interacts with the body\u2019s endocannabinoid system (ECS), an intricate cellular communication network that plays a crucial role in regulating various functions, including sleep, appetite, pain perception, and immune system activity.\r\n<h2>Benefits of CBD for osteoarthritis in dogs<\/h2>\r\nCurrently, in France and across Europe, a wide variety of CBD-based products are available. For humans, there are CBD oils, gummies, teas, and vaping options. For our animal companions, <a href=\"\/?page_id=169547\">CBD oil<\/a> is the most suitable choice, as it can be administered directly under the tongue in animals that tolerate it, such as dogs. Some of CBD\u2019s key properties include:\r\n<ol>\r\n \t<li><strong>Anti-inflammatory properties<\/strong>:\r\nCBD is recognized for effectively combating inflammation. Various studies have shown that CBD has efficacy comparable to traditional anti-inflammatory drugs, yet without the associated adverse side effects. Several specific studies have validated the anti-inflammatory properties of CBD (MECHA et al. 2013, KOZELA et al. 2013, BUCCELLATO et al. 2011, RIBEIRO et al. 2012). A 2016 study revealed that CBD consumption increases the production of the anti-inflammatory cytokine IL-10 in participants (KOZELA et al.).<\/li>\r\n \t<li><strong>Analgesic effect<\/strong>:\r\nThanks to its anti-inflammatory action, CBD helps alleviate associated pain. Many pet owners have reported positive results when using CBD to address pain in animals. A study conducted by the University of Philadelphia, in the United States, suggests that CBD may be effective in managing certain types of pain.<\/li>\r\n \t<li><strong>Improved sleep<\/strong>:\r\nOsteoarthritis can significantly disrupt a dog\u2019s sleep, as pressure from the dog\u2019s body while lying down may intensify pain in affected areas. This causes the dog to wake up and seek a more comfortable position. Studies have shown that CBD oil can prolong both the duration and quality of sleep (Chagas et al. 2013).<\/li>\r\n \t<li><strong>Anxiolytic and stress-reducing effects<\/strong>:\r\nConstant pain, triggered by every movement and even at rest, can negatively affect a dog\u2019s mental health, leading to anxiety disorders. CBD oil, thanks to its calming properties demonstrated in both animals (dogs, cats, etc.) and humans (Campos et al. 2012, Elbatsh et al. 2012), can relieve pain symptoms, thereby reducing anxiety and stress levels.<\/li>\r\n<\/ol>\r\n<h2>Conclusion<\/h2>\r\nCBD presents itself as a natural option for mitigating the symptoms associated with osteoarthritis in dogs. There are reports from owners who have noticed an increase in their dogs\u2019 mobility and overall quality of life. However, it is crucial to remain aware of potential consequences and costs, and it is imperative to consult a veterinarian before administering CBD to your companion animal.\r\n<h2>Bibliography and Digital Sources<\/h2>\r\n<ul class=\"footnotes\">\r\n \t<li>Abrahamov, A., Abrahamov, A., Mechoulam, R. 1995. An efficient new cannabinoid antiemetic in pediatric oncology. Life Sci. 56: 2097\u20132102.<\/li>\r\n \t<li>Bonini, S.A., Premoli, M., Tambaro, S. et alt. 2018. Cannabis sativa: a comprehensive ethnopharmacological review of a medicinal plant with a long history. J. Ethnopharmacol. 227:300-315.<\/li>\r\n \t<li>Bradley, S., Young, S., Bakke, A.M. et alt. 2022. Long-term daily feeding of cannabidiol is well-tolerated by healthy dogs. Front. Vet. Sci. 9: 122-130.<\/li>\r\n \t<li>Brioschi, F.A., Di Cesare, F., Gioeni, D., et alt. 2020. Oral Transmucosal Cannabidiol Oil Formulation as Part of a Multimodal Analgesic Regimen: Effects on Pain Relief and Quality of Life Improvement in Dogs Affected by Spontaneous Osteoarthritis. Animals (Basel) 10 (9): 1505-1510.<\/li>\r\n \t<li>Cluny, N.L., Naylor, R.J,. Whittle, B.A., Javid, F.A. 2008. The effects of cannabidiol and tetrahydrocannabinol on motion-induced emesis in Suncus murinus. Basic Clin. Pharmacol. Toxicol. 103:150\u2013156.<\/li>\r\n \t<li>Della Rocca, G., Di Salvo, A. 2020. Hemp in Veterinary Medicine: From Feed to Drug. Front. Vet. Sci. 7: 387-392.<\/li>\r\n \t<li>Fallahi, S., Bobak, L., Opalinski, S. 2022. Hemp in animal diets Cannabidiol. Animals (Basel) 12 (19): 2541-2543.<\/li>\r\n \t<li>Gamble, L.J., Boesch, J.M., Frye, C.W., et alt. 2018. Pharmacokinetics, safety and clinical efficacy of cannabidiol treatment in osteoarthritic dogs. Front. Vet. Sci. 5: 165-170.<\/li>\r\n \t<li>Garc\u00eda, G., Kube, S., Carrera-Justiz, S. et alt. 2022. Safety and efficacy of cannabidiol-cannabidiolic acid rich hemp extract in the treatment of refractory epileptic seizures in dogs. Front. Vet Sci. 9: 140-145.<\/li>\r\n \t<li>Lima, T.M., Santiago, N.R., Alves E.C.R., et alt. 2022. Use of cannabis in the treatment of animals: a systematic review of randomized clinical trials. Anime. Health Res. Rev. 23 (1): 25-38.<\/li>\r\n \t<li>McGrath, S. 2017. Efficacy of Cannabidiol (CBD) for the Treatment of Canine Epilepsy. Grant of American Brittany Club.<\/li>\r\n \t<li>McGrath, S., Bartner, L.R., Rao, S. et alt. 2019. Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy. J. Am. Vet. Med. Assoc. 254 (11): 1301-1308.<\/li>\r\n \t<li>Mechoulam R. 2005. Plant cannabinoids: a neglected pharmacological treasure trove. Br J Pharmacol. 146: 913\u2013915.<\/li>\r\n \t<li>Morrow, L., Belshaw, Z. 2022. Is cannabidiol an effective supplementary treatment for reducing paining dogs with osteoarthritis?. Vet. Rec. 191 (10): 420-421.<\/li>\r\n \t<li>Naciones Unidas. 1961. Convenci\u00f3n \u00fanica sobre estupefacientes. Publicaciones de la ONU. New York. 25 pp<\/li>\r\n \t<li>Parker, L.A., Rock, E.M., Limebeer, C. L. 2011. Regulation of nausea and vomiting by cannabinoids. Br. J. Pharmacol. 163 (7): 1411-1422.<\/li>\r\n \t<li>Perry, M.S. 2019. Don\u2019t Fear the Reefer-Evidence Mounts for Plant-Based Cannabidiol as Treatment for Epilepsy. Epilepsy Curr. 19 (2): 93-95.<\/li>\r\n \t<li>S\u00e1nchez-Valverde, M.A. 2014. Patolog\u00eda del aparato locomotor. Editorial Diego Mar\u00edn Librero Editor. Murcia. 429 pp.<\/li>\r\n \t<li>S\u00e1nchez-Valverde, M.A., Navarro Alberola, A., Murciano P\u00e9rez, J. 2015. Afecciones ortop\u00e9dicas y articulares de la extremidad anterior. Editorial Diego Mar\u00edn Librero Editor. Murcia. 367 pp.<\/li>\r\n \t<li>S\u00e1nchez-Valverde, M.A., Navarro Alberola, A., Murciano P\u00e9rez, J. 2015. Afecciones ortop\u00e9dicas y articulares de la extremidad posterior. Editorial Diego Mar\u00edn Librero Editor. Murcia. 440 pp.<\/li>\r\n \t<li>S\u00e1nchez-Valverde, M.A., Murciano, J., Navarro, A., Paredes, J. 2016. Cirug\u00eda de la columna vertebral. Editorial Diego Mar\u00edn Librero Editor. Murcia. 516 pp.<\/li>\r\n \t<li>S\u00e1nchez-Valverde, M.A., Zilberchstein, J., Carrillo S\u00e1nchez, J.D. 2022. Osteoartrosis: Introducci\u00f3n, concepto y artrolog\u00eda en general. Canis y Felis 20: 6-13.<\/li>\r\n \t<li>Szaflarski, J.P., Bebin, E.M., Comi, A.M. et alt. 2018. CBD EAP Study Group. Epilepsia 59 (8):1540-1548.<\/li>\r\n \t<li>Van Sickle, M.D., Oland, L.D., HO, W., et alt. 2001. Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret. Gastroenterology. 121:767\u2013774.<\/li>\r\n \t<li>Vaughn, D., Paulionis, L., Kulpa, J. 2021. Randomized, placebo-controlled, 28-day safety and pharmacokinetics evaluation of repeated oral cannabidiol administration in healthy dogs. Am. J. Vet. Res. 82 (5): 405-416.<\/li>\r\n \t<li>Wakshlag, J., Schwark, W., Deabold, K. et alt. 2020. Pharmacokinetics of Cannabidiol, Cannabidiolic Acid, \u03949-Tetrahydrocannabinol, Tetrahydrocannabinolic Acid and Related Metabolites in Canine Serum After Dosing With Three Oral Forms of Hemp Extract. Front. Vet Sci. 7: 505-508.<\/li>\r\n \t<li>Wang, T., Zakharov, A., Gomez, B., et alt. 2022. Serum cannabinoid 24h and 1week steady state pharmacokinetic assessment in cats using a CBD\/CBDA rich hemp paste. Front. Vet. Sci. 9: 225-236.<\/li>\r\n \t<li>Yu, C.H.J., Vasantha Rupasinghe, H.P. 2021. Cannabidiol-based natural health products for companion animals: Recent advances in the management of anxiety, pain, and inflammation. Res. Vet. Sci. 140: 38-46.<\/li>\r\n \t<li>Zilberchstein, J., S\u00e1nchez-Valverde, M.A. 2014. Fisioterapia y rehabilitaci\u00f3n en veterinaria. Editorial Diego Mar\u00edn Librero Editor. Murcia. 347 pp.<\/li>\r\n<\/ul>\r\n\r\n<div style=\"border: 1px solid #fcb900;\">\r\n<p style=\"margin: 10px 10px 10px 10px;\"><strong>SOUTHERN PHARMA SPAIN S.L no asumir\u00e1 ninguna responsabilidad derivada del uso por terceros del contenido del sitio web y podr\u00e1 ejercitar todas las acciones civiles o penales que le correspondan en caso de infracci\u00f3n de estos derechos por parte del usuario. Est\u00e1 absolutamente prohibido, el uso del sitio web o de alguno de sus elementos con fines il\u00edcitos. Los beneficios y propiedades de cbd que se pudieran leer en la web www.gorillagrillz.com , en ning\u00fan caso se atribuyen a los productos que se venden en la web. Los productos de CBD no son medicamentos ni deben sustituir los tratamientos con estos. Lo que puedes leer en nuestra web no son afirmaciones m\u00e9dicas oficiales sino referencias a estudios precl\u00ednicos. Si tienes cualquier duda, puedes consultar con un personal sanitario profesional. Te recordamos que en Espa\u00f1a los productos de CBD son de uso t\u00f3pico. Todos los productos tienen anal\u00edticas de THC&lt;0.2% de acuerdo al real decreto 1729\/1999.<\/strong><\/p>\r\n\r\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Osteoarthritis frequently occurs in canines, typically associated with pain and restricted mobility. Recently, CBD for dogs (Cannabidiol) has emerged as a promising natural option to alleviate symptoms related to osteoarthritis in dogs. It is essential to emphasize the importance of consulting a veterinarian before administering CBD to pets, especially in the context of specific health [&hellip;]<\/p>\n","protected":false},"author":5132,"featured_media":170533,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[4805],"tags":[],"class_list":["post-170531","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cbd-pets-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/posts\/170531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/users\/5132"}],"replies":[{"embeddable":true,"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/comments?post=170531"}],"version-history":[{"count":0,"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/posts\/170531\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/media\/170533"}],"wp:attachment":[{"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/media?parent=170531"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/categories?post=170531"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.gorillagrillz.com\/en\/wp-json\/wp\/v2\/tags?post=170531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}